tag:rroeder.nd.edu,2005:/newsRoeder Research Lab | News2020-07-14T16:50:00-04:00tag:rroeder.nd.edu,2005:News/1280172020-07-14T16:50:00-04:002020-08-04T16:51:12-04:00Notre Dame launches materials science and engineering doctoral degree program<p>Students can now earn a distinctive, interdisciplinary doctoral degree in materials science and engineering through the College of Engineering and the College of Science.</p><p>The University of Notre Dame has announced a new interdisciplinary doctoral program in <a href="https://nano.nd.edu/materials-science/phd-program/">Materials Science and Engineering</a>. Students can now earn a distinctive, interdisciplinary degree in materials science and engineering through the College of Engineering and the College of Science.</p>
<p>“Materials science and engineering is central to a number of academic disciplines and careers, making it an important field of study to offer to graduate students at Notre Dame,” said <a href="https://graduateschool.nd.edu/about/laura-carlson/">Laura Carlson</a>, vice president and associate provost and dean of the <a href="https://graduateschool.nd.edu/">Graduate School</a>. “The new Materials Science and Engineering doctoral program will give current students the opportunity to expand on their degrees and also attract prospective graduate students who are determined to build their expertise in the field of materials science and engineering.”</p>
<p>Faculty from the <a href="https://engineering.nd.edu/">College of Engineering</a> and the <a href="https://science.nd.edu/">College of Science</a> have put together a distinctive program to equip students with the skills needed to address complex problems, such as access to clean water and energy efficiency. The program is committed to building an energetic materials community in which students and faculty collaborate to answer questions at the forefront of science and engineering.</p>
<p>Additionally, this new program aims to enhance student understanding in materials science and engineering by building on Notre Dame’s <a href="https://nano.nd.edu/materials-science/">background and expertise</a> in this area. </p>
<p>“The University has a long history in materials science and engineering, which dates back to the Department of Metallurgy that began in 1933. Since then, Notre Dame has maintained signature materials research efforts in electronic materials, actinides, polymers, and biomaterials,” said <a href="https://engineering.nd.edu/profiles/aseabaugh">Alan Seabaugh</a>, chair of the <a href="https://nano.nd.edu/materials-science/leadership/">executive committee for the doctoral program</a>, director of <a href="https://nano.nd.edu/">Notre Dame Nanoscience and Technology</a> (NDnano), and Frank M. Freimann Professor of Electrical Engineering. “This new graduate program recognizes the importance of materials in scientific inquiries and engineering innovation.” </p>
<p>The program will coordinate courses offered across the Colleges of Engineering and Science including <a href="https://nano.nd.edu/materials-science/courses/">courses</a> in materials synthesis, growth, physics, chemistry, characterization, and engineering. Students apply through one of these departments and programs: Aerospace and Mechanical Engineering, Bioengineering, Chemical and Biomolecular Engineering, Chemistry and Biochemistry, Civil & Environmental Engineering & Earth Sciences, Electrical Engineering, or Physics. </p>
<p>Students in the Materials Science and Engineering doctoral program will craft a research plan, working with dissertation advisors who bridge departments and colleges around problems where materials are a central focus. Students who successfully complete both department and/or program and Materials Science and Engineering requirements will earn a Materials Science and Engineering Ph.D. in their discipline.</p>
<p>Competitive one-year, non-renewable fellowships for students are available. These <a href="https://nano.nd.edu/materials-science/fellowships/">prestigious fellowships</a> provide a year of support for students, providing faculty and their research groups flexibility for writing proposals and expanding their programs. </p>
<p>Notre Dame’s Materials Science and Engineering doctoral program was developed by faculty in the College of Engineering, College of Science, and the following Notre Dame Research units: <a href="https://advanceddiagnostics.nd.edu/">Advanced Diagnostics & Therapeutics</a>, the <a href="https://harpercancer.nd.edu/">Harper Cancer Research Institute</a>, the <a href="https://energy.nd.edu/">Center for Sustainable Energy at Notre Dame</a>, and NDnano. It is administered by NDnano.</p>
<p>To learn more about materials science and engineering at Notre Dame and the interdisciplinary doctoral program, please visit <a href="https://nano.nd.edu/materials-science/">https://nano.nd.edu/materials-science/</a>. </p>
<p>Contact:</p>
<p>NDnano / University of Notre Dame</p>
<p><a href="mailto:MSE-list@nd.edu">MSE-list@nd.edu</a> / 574.631.0279</p>
<p><a href="https://nano.nd.edu/">nano.nd.edu</a> / <a href="https://twitter.com/NDnano">@NDnano</a></p>
<p>About Notre Dame Research:</p>
<p>The University of Notre Dame is a private research and teaching university inspired by its Catholic mission. Located in South Bend, Indiana, its researchers are advancing human understanding through research, scholarship, education, and creative endeavor in order to be a repository for knowledge and a powerful means for doing good in the world. For more information, please see <a href="https://research.nd.edu/">research.nd.edu</a> or <a href="https://twitter.com/UNDResearch">@UNDResearch</a>.</p>
<p class="attribution">Originally published by <span class="rel-author">Brandi Wampler</span> at <span class="rel-source"><a href="https://nano.nd.edu/news-events/news/notre-dame-launches-materials-science-and-engineering-doctoral-degree-program/">nano.nd.edu</a></span> on <span class="rel-pubdate">July 14, 2020</span>.</p>Brandi Wamplertag:rroeder.nd.edu,2005:News/1280162020-01-29T16:00:00-05:002020-08-04T16:52:11-04:00New technology could help tackle antibiotic resistance<p>According to the World Health Organization, one of the biggest health threats around the world is antibiotic-resistant bacteria and researchers at the University of Notre Dame are working to combat this problem by developing a nanoparticle-based system.</p><p>According to the World Health Organization, one of the biggest health threats around the world is antibiotic-resistant bacteria. Every day people use antibiotics to prevent or fight back against infection, but as bacteria evolve and develop resistance, diseases such as pneumonia and tuberculosis are becoming harder to treat. </p>
<p>Researchers at the University of Notre Dame are working to combat this problem by looking to bacteriophages or phages, which are viruses that infect bacteria. Phages infect bacteria, similarly to how bacteria infect people, but bacteria have yet to develop resistance to these viruses. In a <a href="https://pubs.rsc.org/en/content/articlelanding/2019/na/c9na00461k">study published in Nanoscale Advances</a>, the researchers have shown the efficacy of a new nanoparticle-based system that mimics how phages attack and kill bacteria.</p>
<p>“Instead of chasing the next antibiotic, we want to create a system that can treat infection and is an option that bacteria can’t develop resistance to,” said <a href="https://engineering.nd.edu/profiles/pnallathamby">Prakash Nallathamby</a>, research assistant professor of aerospace and mechanical engineering and directing author of the study. “In our initial attempt, our team was able to kill several different types of clinically relevant bacteria with varying degrees of success.”</p>
<p>The phage-mimicking nanoparticle system consists of silver-coated gold nanoparticles distributed randomly on a silica core. Once created, the system was tested for its ability to kill four bacteria types that are known to have antibiotic-resistant strains: <em>Corynebacterium striatum</em>, <em>Enterococcus faecalis</em>, <em>Pseudomonas aeruginosa</em>, and <em>Staphylococcus aureus</em>. These various bacteria cause a number of health issues including prosthetic device infections, sepsis, meningitis, and blood infections.</p>
<p>Initial tests showed that the nanoparticle system was 50 to 90 percent effective in killing the bacteria strains for all but <em>Pseudomonas aeruginosa</em>, which was only 21 percent effective. However, when the researchers combined the nanoparticle system with peptides that also have antibacterial activity, the system was 100 percent effective at killing the bacteria.</p>
<p>“By incorporating a biological element, we were able to make the nanoparticles more effective in eliminating the bacteria in initial testing,” said Nallathamby. “Now, we are actively looking to partner with an organization that would advance this system to a clinical study.”</p>
<p>The lead author of this study was postdoctoral researcher Juliane Hopf. Other coauthors include Shaun W. Lee, Monahan Family Associate Professor of Rare and Neglected Diseases; Ryan Roeder, professor of aerospace and mechanical engineering; Joshua Shrout, associate professor of civil & environmental engineering & earth sciences; graduate student Katelyn Carothers; and undergraduate researchers Margo Waters and Veronica Kalwajtys. The study was supported by the strategic research initiatives <a href="https://advanceddiagnostics.nd.edu/">Advanced Diagnostics and Therapeutics</a> and the <a href="https://nano.nd.edu/">Center for Nano Science and Technology</a> (NDnano). Additionally, the study was partially funded by the <a href="https://ctsi.nd.edu/">Indiana Clinical and Translational Sciences Institute</a>. The intellectual property from these studies is protected by a patent application filed by the <a href="https://ideacenter.nd.edu/">IDEA Center</a> at the University of Notre Dame.</p>
<p>To read the paper, please visit <a data-saferedirecturl="https://www.google.com/url?q=https://pubs.rsc.org/en/content/articlelanding/2019/na/c9na00461k&source=gmail&ust=1580421003906000&usg=AFQjCNEiuNwDDS3eOr5nz6czcfg8AvYW-g" href="https://pubs.rsc.org/en/content/articlelanding/2019/na/c9na00461k" target="_blank">https://pubs.rsc.org/en/content/articlelanding/2019/na/c9na00461k</a>.</p>
<p>Advanced Diagnostics and Therapeutics (AD&T) is a research initiative dedicated to combating disease, promoting health, and safeguarding the environment. The initiative fosters cross-cutting exploration and integration across multiple disease areas and health challenges. By fostering a community of researchers spanning disciplines at the University of Notre Dame, AD&T aims to accelerate the research, identify and develop bold new ideas with real-world impact, and support the training of young researchers. To learn more, please visit <a href="https://advanceddiagnostics.nd.edu/">advanceddiagnostics.nd.edu</a>.</p>
<p>NDnano promotes collaborative research in science and engineering to address unsolved scientific and technical questions with an aim to promote the greater good. Advances in imaging and characterization, synthesis, growth, and nanofabrication are enabling breakthroughs in all science and engineering disciplines. NDnano is where Notre Dame faculty, researchers, and students meet to broaden understanding, discuss multidisciplinary research opportunities, and shape future research directions. To learn more, please visit <a href="https://nano.nd.edu/">nano.nd.edu</a>.</p>
<p>Contact:</p>
<p>Brandi Wampler / Research Communications Specialist</p>
<p>Notre Dame Research / University of Notre Dame</p>
<p><a href="mailto:brandiwampler@nd.edu">brandiwampler@nd.edu</a> / 574.631.8183</p>
<p><a href="https://research.nd.edu/">research.nd.edu</a> / <a href="https://twitter.com/UNDResearch">@UNDResearch</a></p>
<p>About Notre Dame Research:</p>
<p>The University of Notre Dame is a private research and teaching university inspired by its Catholic mission. Located in South Bend, Indiana, its researchers are advancing human understanding through research, scholarship, education, and creative endeavor in order to be a repository for knowledge and a powerful means for doing good in the world. For more information, please see <a href="https://research.nd.edu/">research.nd.edu</a> or <a href="https://twitter.com/UNDResearch">@UNDResearch</a>.</p>
<p class="attribution">Originally published by <span class="rel-author">Brandi Wampler</span> at <span class="rel-source"><a href="https://research.nd.edu/news/new-technology-could-help-tackle-antibiotic-resistance/">research.nd.edu</a></span> on <span class="rel-pubdate">January 22, 2020</span>.</p>Brandi Wamplertag:rroeder.nd.edu,2005:News/1027322017-09-11T09:00:00-04:002019-08-14T09:55:50-04:00Researchers Tackle Ovarian Cancer Using a Multidisciplinary Approach<p>September is National Ovarian Cancer Awareness Month. Ovarian cancer is among the most deadly of all cancers, though because of less awareness, most cities won’t be as blanketed in teal (ovarian cancer’s awareness color) as they are bathed in pink for October’s focus on breast cancer. But researchers at the Harper Cancer Research Institute, a collaboration between the University of Notre Dame and the Indiana University School of Medicine South Bend, are working with community partners to not only foster awareness of ovarian cancer but also to develop tests for early detection, create novel chemotherapies, and target a cure.</p><p>Nancy White of Mishawaka was 41 in 1996, living life to the fullest — winning dance contests and going on cruises and minding two middle-school children — when she was dealt a blow that altered the course of her life.</p>
<p>Her yearly pap smear results showed something shocking and highly unusual: ovarian cancer cells. White describes the discovery as “divine intervention, because that day a tumor must have burst, and the cancer cells must have gone into the fallopian tubes, and that’s how I got a diagnosis.” Because of this extremely rare form of detection (a pap smear is a screening test for cervical cancer … not for ovarian cancer), along with chemotherapy and surgery, White, unlike the majority of women diagnosed with the disease, is alive 21 years later.</p>
<p>September is National Ovarian Cancer Awareness Month. Ovarian cancer is among the most deadly of all cancers, though because of less awareness, most cities won’t be as blanketed in teal (ovarian cancer’s awareness color) as they are bathed in pink for October’s focus on breast cancer. But researchers at the <a href="https://harpercancer.nd.edu/" target="_blank">Harper Cancer Research Institute</a>, which is a collaboration between the University of Notre Dame and the Indiana University School of Medicine South Bend (IUSM-SB), are working with community partners to not only foster awareness of ovarian cancer, but to develop tests for early detection, create novel chemotherapies, and target the Holy Grail: A cure.</p>
<p>There is no singular “cure for cancer,” because there are many types of cancer cells. Even within specific cancers, like ovarian, there are different varieties, some of which succumb more easily to treatment. “The goal with chemotherapy, of course, is a cure,” says <a href="http://chemistry.nd.edu/people/karen-cowden-dahl/" target="_blank">Karen Cowden Dahl</a>, who studies the genetic components of ovarian cancer. “But with ovarian cancer, the goal is more to extend life; very few people are cured,” she notes.</p>
<p>Ovarian cancer has a 46-percent, five-year survival rate, but that percentage includes patients with more rare and less aggressive forms of ovarian cancer. Most patients have late-stage, high-grade serous ovarian carcinoma (HGSC), and the five-year survival for these women is less than 30 percent, describes Cowden Dahl, who is adjunct associate professor of chemistry and biochemistry at Notre Dame and associate professor of biochemistry and molecular biology at IUSM-SB.</p>
<p>Ovarian cancer is deadly for many reasons, according to cancer researcher <a href="http://chemistry.nd.edu/people/sharon-stack/" target="_blank">Sharon Stack</a>. Stack, the Kleiderer-Pezold Professor of Biochemistry at Notre Dame and Ann F. Dunne and Elizabeth Riley Director, Harper Cancer Research Institute, says symptoms of ovarian cancer are very subtle – bloating, abdominal fullness, decreased hunger, and abdominal cramping. Even those won’t show up until the disease is in advanced stages. Also, ovarian cancer tends to respond to initial chemotherapies but is prone to return later, and is more lethal when it does.</p>
<p>Then there is the method by which ovarian cancer cells spread. They quickly invade and metastasize throughout the entire peritoneal cavity — the area within the abdominal wall — rather than leisurely traveling the blood stream and tackling bone and the brain like breast cancer does in its late stages. “The ovarian cancer cells stick to everything. They stick to the peritoneal cavity and the intestines and liver and most women actually die from starvation because their bowels become obstructed when the tumors press into their intestines. This is really severely unpleasant, to put it mildly,” Stack notes, pointing to an autopsy photo on her desk of a patient’s intestines pocked with an overwhelming number of white, cottage-cheesy structures.<br>
<br>
Stack strives to discover why ovarian cancer cells are so adept at spreading, and published three articles plus a review article of her work this summer, two of which landed on journal covers. Two additional papers are nearing publication. “Something tells the cells to detach from the tumor and they float in the peritoneal cavity, and then there’s some signal, we don’t know what it is, that says, ‘stop floating and start sticking’ to things like the lining of the intestine. The cells stick, and they invade and start to divide like crazy.” Her studies have demonstrated that ovarian cancer in older mice, obese mice, and virgin mice is more likely to metastasize quickly, so those discoveries might hold some clues about how the disease progresses. “Now we have some mechanistic pathways to chase here,” she says.</p>
<p>While Stack and Cowden Dahl focus on metastasis, <a href="https://engineering.nd.edu/profiles/rroeder" target="_blank">Ryan K. Roeder</a>, professor in the <a href="http://bme.nd.edu/" target="_blank">bioengineering graduate program</a> and in the <a href="http://ame.nd.edu/" target="_blank">Department of Aerospace and Mechanical Engineering</a> at Notre Dame, is investigating methods of early detection. “Breast cancer is treatable because of early detection by mammography. The problem with ovarian cancer is that we lack a means for early detection. If we can detect it early, then we can treat it more effectively,” he says.<br>
<br>
Most cancer cells overexpress, or make too many copies, of certain proteins. It is possible to target cancer cells if an agent can detect the antigens that are carried on those proteins. Roeder’s lab creates gold nanoparticles that are “loaded” with an antibody that targets the antigen. Patients would be administered the nanoparticles through an IV, then undergo a Computed Tomography (CT) scan where radiologists could detect the location of the gold nanoparticles, and therefore the targeted ovarian cancer cells, possibly before large tumors form.<br>
<br>
Though these researchers and others at the both universities are focused on various aspects of the disease, it’s imperative that women trust their instincts and notify their physicians if they feel there’s something wrong, says Nonyem Onujiogu, a South Bend gynecologic oncologist who works with <a href="https://harpercancer.nd.edu/research-programs/tissue-biorepository/" target="_blank">Harper Cancer Research Institute’s Tissue Biorepository</a>, sending samples to be banked after patients have consented. White, the cancer survivor from Mishawaka, was fortunate because her ovarian cancer was detected before she experienced outward physical symptoms. Unfortunately, many women might be hesitant to share the vague abdominal symptoms with their doctors, hoping their symptoms will resolve, Onujiogu says.<br>
<br>
“You need to be persistent in reporting symptoms that do not resolve. It’s about trusting your gut. If you have a symptom for more than two weeks, and you’re very worried, communicate your symptoms and your concern to your doctor. It is okay to ask if there is any indication for further testing,” she stresses, adding, “I’m not just treating a disease … I’m treating a person.”<br>
<br>
Harper Cancer Research Institute’s collaborative approach toward ovarian cancer will eventually lead to breakthroughs with the disease, Notre Dame and Indiana University researchers hope. “Cures don’t come from one person; cures come from the interface of different technologies,” Cowden Dahl says.<br>
<br>
Roeder, who has been working in the field of biomedical research for 16 years, agrees. “Engineers … we make things, and make things better. The big challenges facing us in society — health care, cancer, energy — there’s no one academic discipline that holds the key. We need engineers. We need biologists. We need clinicians. I could go on and on.”<br>
<br>
White, who co-founded a local support group called Gyna Girls to help women with gynecological cancers, keeps in touch with many of Notre Dame’s cancer researchers, and some have spoken at her meetings. For White, continuing to educate herself and others is key, and Notre Dame’s and Indiana University School of Medicine–South Bend’s commitment to ovarian cancer is essential. “I keep trying to help women live; you have to live and have hope that researchers will find a cure,” she says.<br>
<br>
“We are excited about the advancements we’ve made so far through our research,” Stack says. “By working together, we will continue to identify pathways that will lead to better treatment outcomes in the future.”<br>
<br>
<em>— Deanna Csomo McCool, College of Science, University of Notre Dame</em></p>Deanna Csomo McCooltag:rroeder.nd.edu,2005:News/1027282016-10-28T09:00:00-04:002019-08-14T09:48:20-04:00Fighting for Better Cancer Detection<p>A mammogram’s ability to detect tumors at early stages has made breast cancer one of the most treatable forms of cancer. Still there are almost 50,000 missed diagnoses every year. Engineering professor Ryan K. Roeder has devised a way in which gold nanoparticles can be injected into the breast and attach to indicators of cancer, so they can be clearly seen.</p><p><strong>It seems black and white: Either you have cancer or you don't. But for many women the answer is gray. Hazy mammogram gray.</strong><br>
<br>
In the United States alone, there are nearly 240,000 breast cancer diagnoses each year, and one in eight women will develop breast cancer at some point in her lifetime. To date, mammograms are the best diagnostic technology for breast cancer. A mammogram’s ability to detect tumors at early stages has made breast cancer one of the most treatable forms of cancer, but there are still almost 50,000 missed diagnoses every year.<br>
<br>
For many women, that missed diagnosis comes from having dense breast tissue which prohibits clear results from a basic mammogram. Breasts are made up of three types of tissue: fatty, fibrous and glandular. Most women have a mix of the three, but if the fibrous and glandular tissue outweigh the fatty tissue, women are classified as having dense breasts, wherein lies the problem. Fatty tissue appears transparent on X-rays which makes abnormalities like microcalcifications and tumors easy to see. However, fibrous and glandular tissue are less transparent which makes it difficult to detect abnormalities in a mammogram.</p>
<p><iframe allow=";" allowfullscreen="" frameborder="0" height="360" src="https://www.youtube.com/embed/mJ7D8t_XaxE?rel=0" width="640"></iframe></p>
<p>As a double whammy, having dense breast tissue doesn’t only make cancer more difficult to diagnose, it’s also linked to an increased risk of getting breast cancer in the first place.<br>
<br>
That’s where Notre Dame engineering professor Ryan K. Roeder comes in. Roeder has devised a way in which gold nanoparticles can be injected into the breast and attach to indicators of cancer, like microcalcifications. Because gold is a heavy metal, in an X-ray or mammogram it will be seen clearly, even in dense tissue.<br>
<br>
“The current clinical data suggests that the best hope for controlling breast cancer is early detection by mammography,” Roeder says.</p>
<p>“We could administer, through a needle in the breast, a contrast agent that’s going to help us better determine if this [tissue] is really something we need to be concerned about or not,” he explains. “The contrast agent will allow us to see things that might be masked by dense breast tissue, and will allow us to rule out false positives and negatives.”</p>
<p>The gold nanoparticles can also be attached to antibodies which target specific receptors on cancer cells, such as HER2, which are overexpressed in certain types of breast cancer. Roeder hopes physicians will be able to target the tumor cells themselves to make more precise diagnoses and monitor tumor growth and metastasis.<br>
<br>
One of the reasons this research is so clinically appealing is that it is cost effective. Currently, if a woman has a mammogram with questionable results, she must undergo a biopsy which is costly for hospitals and often traumatic for patients. Roeder explains that because his research focuses on the gold contrast agent instead of a different screening process, hospitals will not need to purchase new technology to get clearer answers. When a question arises, doctors can use existing mammography and X-ray systems to seek out the gold once it’s been injected. Even the gold, he asserts, is used in such small quantities that it would cost less than $20 per injection.<br>
<br>
“We’re talking about using the same mammography systems that are already used nationwide for screening and making them better,” he says. His hope is that because this concept uses existing technology — most other options do not — it may stand a chance in clinical trials and eventually be available in hospitals.<br>
<br>
What makes Roeder stand apart in the fight against breast cancer, though, is his unique point of view. He isn’t a medical professional — at the outset, he didn’t even know much about breast cancer. But as an engineer he’s looking at the problem of breast cancer from a different angle.<br>
<br>
In fact, breast cancer wasn’t his initial target. Roeder designed the gold nanoparticles to target calcium for an entirely different project in orthopedics where it would be used to detect cracks in bone. But when applied, the gold didn’t show brightly against dense bone, even though the calcium targeting was effective. So he thought about where there might be calcium deposits in soft tissue where this technology could be better applied. Breast cancer became the obvious choice.<br>
<br>
From there he set out to learn as much as possible about breast cancer. He went to the Harper Cancer Research Institute and met Tracy Vargo-Gogola, an adjunct assistant professor at Notre Dame and a lecturer at IU School of Medicine–South Bend. She taught him about breast cancer, and he introduced his contrast as a possible solution to the problem of inaccurate mammograms. Despite his inexperience in the field, he garnered immediate support.</p>
<p>In time, partnerships with Saint Joseph Regional Medical Center, the Notre Dame Integrated Imaging Facility and the Kelly Cares Foundation followed. For Pacqui Kelly, the desire to catch breast cancer early comes from personal experience. Twice now she’s been diagnosed with the disease, but because she was proactive, she received appropriate treatment and then given a clean bill of health. She realizes, though, that some women aren’t as lucky. Kelly Cares and Roeder’s lab are currently partnering to build a human-scale model of synthetic materials so that Roeder can most effectively simulate what his contrast will do in humans.</p>
<p>Meanwhile, Roeder is also looking at new and advanced imaging technologies, such as spectral computed tomography, that allow color imaging of different contrast agents and tissues. Roeder’s lab is designing and evaluating new imaging probes to leverage the capabilities of this new imaging technology. <br>
<br>
“This would be incredibly powerful — transformative, I would say — for oncologists and surgeons as they’re diagnosing, planning treatments and following treatments for cancer,” he says.<br>
<br>
Roeder’s project is far from the finish line, but optimism in this fight against breast cancer is high. With luck, partnerships and persistence, the best way to think pink may involve thinking gold. </p>Nina Weldingtag:rroeder.nd.edu,2005:News/1027292016-05-04T09:50:00-04:002019-08-14T09:56:56-04:002016 Internal Grant Program Awardees Announced<p><a href="http://research.nd.edu/">Notre Dame Research</a> has provided more than 35 researchers with awards from the <a href="https://research.nd.edu/our-services/funding-opportunities/faculty/internal-grants-programs/">Internal Grants Program</a> for 2016. The grant awardees spanned the University in four program categories: Faculty Research Support (Initiation), Faculty Research Support (Regular), Equipment Restoration and Renewal, and Library Acquisitions.</p><p><a href="http://research.nd.edu/">Notre Dame Research</a> has provided more than 35 researchers with awards from the <a href="https://research.nd.edu/our-services/funding-opportunities/faculty/internal-grants-programs/">Internal Grants Program</a> for 2016. The grant awardees spanned the University in four program categories: Faculty Research Support (Initiation), Faculty Research Support (Regular), Equipment Restoration and Renewal, and Library Acquisitions.</p>
<p>In discussing the grants, Vice President for Research <a href="https://research.nd.edu/staff/robert-j-bernhard/">Robert J. Bernhard</a> said, “The University is pleased to be able to support these outstanding programs of research and scholarship. The awards for this year represent just a sampling of the excellent proposals received for these four competitions. We look forward to the results and the contributions of these projects to the scholarly record of Notre Dame.”</p>
<p>The 2016 Faculty Research Support Initiative Grant Program awardee are:</p>
<p> </p>
<ul>
<li>
<p><a href="http://physics.nd.edu/people/faculty/timothy-c-beers/">Timothy Beers</a>, chair of astrophysics and professor of physics, and <a href="http://physics.nd.edu/people/faculty/vinicius-m-placco/">Vinicius Placco</a>, research assistant professor of astrophysics, Identification of Carbon-Enhanced Metal-Poor Stars from S-<span class="caps">PLUS</span> Photometry using Artificial Neural Networks</p>
</li>
<br>
<li>
<br>
<a href="https://engineering.nd.edu/profiles/bgary">Gary Bernstein</a>, Frank M. Freimann Chair Professor of Electrical Engineering, and <a href="http://chemistry.nd.edu/people/marya-lieberman/">Marya Lieberman</a>, associate professor of chemistry and biochemistry, Rapid Thermal Processing of <span class="caps">DNA</span> Nanostructures on Silicon for Formation of Self-Aligning p-n Junctions</li>
<br>
<li>
<br>
<a href="http://physics.nd.edu/people/faculty/manoel-couder/">Manoel Couder</a>, assistant professor of experimental nuclear physics, and <a href="http://physics.nd.edu/people/postdocs-visiting-scholars-visiting-students/">Matt Smylie</a>, postdoctoral research assistant of physics, Cross-disciplinary Investigation of Increased Superconducting Current via Particle Irradiation</li>
<br>
<li>
<br>
<a href="http://ftt.nd.edu/faculty-staff/faculty-staff-by-alpha/donald-crafton/">Donald Crafton</a>, the Joseph and Elizabeth Robbie Professor of Film, Television, and Theatre, Digital Reanimation of a Legendary Film Performance: Phase I</li>
<br>
<li>
<br>
<a href="http://politicalscience.nd.edu/faculty/faculty-list/sarah-daly/">Sarah Daly</a>, assistant professor of political science, Civilian Support for Political Actors with Coercive Legacies</li>
<br>
<li>
<br>
<a href="http://cslc.nd.edu/about/faculty-staff/hana-kang/">Hana Kang</a>, associate professor of the practice of east Asian languages and cultures, Language Learners’ Cognitive Processing and Production in Chinese and Korean Writings: The Analysis of Eye-Movement and Handwriting Tracking Data</li>
<br>
<li>
<br>
<a href="http://music.nd.edu/people/faculty/john-liberatore/">John Liberatore</a>, assistant professor of music theory and composition, Extended Techniques, Interactive Electronics, and Musical Composition for Benjamin Franklin’s Glass Harmonica</li>
<br>
<li>
<br>
<a href="http://acms.nd.edu/people/faculty/jun-li/">Jun Li</a>, assistant professor of applied and computational mathematics and statistics, Developing Statistical Methods for Cancer Research based on <span class="caps">RNA</span>-Seq and Single-Cell <span class="caps">RNA</span>-Seq Data</li>
<br>
<li>
<br>
<a href="https://crc.nd.edu/index.php/services/29-crc/about/people/ci-group">Cheng Liu</a>, research assistant professor of psychology, Hierarchical Deep Learning Modeling for Cognitive Diagnostic Assessment</li>
<br>
<li>
<br>
<a href="https://engineering.nd.edu/profiles/kmatous">Karel Matous</a>, associate professor of computational mechanics in aerospace and mechanical engineering; <a href="https://engineering.nd.edu/profiles/amukasyan">Alexander Mukasyan</a>, research professor of chemical and biomolecular engineering; and <a href="https://engineering.nd.edu/profiles/asalvadori">Alberto Salvadori</a>, research assistant professor of aerospace and mechanical engineering, BatterieX: Experiments, Modeling, Simulations towards the Design of Batteries under Extreme Conditions</li>
<br>
<li>
<br>
<a href="http://biology.nd.edu/people/miguel-morales/">Miguel Morales</a>, assistant professor of molecular parasitology in the biological sciences, Drug Resistance in Leishmania Clinical Isolates from India</li>
<br>
<li>
<br>
<a href="http://irishstudies.nd.edu/faculty/faculty-fellows/amy-mulligan/">Amy Mulligan</a>, assistant professor of Irish language and literature, A Landscape of Words: Ireland, Britain and Spatial Poetics of the North Atlantic Archipelago from 700-1300</li>
<br>
<li>
<br>
<a href="http://politicalscience.nd.edu/faculty/faculty-list/susanne-wengle/">Susanne Wengle</a>, assistant professor of political science, Setting The Table, Market Regulations and Food Systems in Russia and the US: The Case of California</li>
</ul>
<p>Awardees for the 2016 Faculty Support Regular Grant Program are:</p>
<p> </p>
<ul>
<li>
<p><a href="https://theology.nd.edu/people/faculty/peter-j-casarella/">Peter Casarella</a>, associate professor of systematic theology, and <a href="https://theology.nd.edu/people/faculty/timothy-matovina/">Timothy Matovina</a>, professor of theology and co-director of the Institute for Latino Studies, <em>Theology of the People: </em>Global Perspectives on the Thought of Pope Francis</p>
</li>
<br>
<li>
<br>
<a href="https://engineering.nd.edu/profiles/pflynn">Patrick J. Flynn</a>, Duda Family Professor of Engineering, and <a href="http://www.und.com/genrel/geoffrey_puls_848903.html">Geoffrey Puls</a>, assistant strength & conditioning coach for Notre Dame Athletics, Markerless Video Analytics for Athletic Performance Characterization</li>
<br>
<li>
<br>
<a href="https://www.nd.edu/about/leadership/council/william-lies/">Rev. William Lies, C.S.C.</a>, Vice President for Mission Engagement and Church Affairs, and <a href="http://history.nd.edu/faculty/directory/john-van-engen/">John Van Engen</a>, Andrew V. Tackles Professor of Medieval History, The Promise of the Vatican Library</li>
<br>
<li>
<br>
<a href="http://politicalscience.nd.edu/faculty/faculty-list/sebastian-rosato/">Sebastian Rosato</a>, associate professor of political science, The Road to Hell? Intentions in International Politics</li>
<br>
<li>
<br>
<a href="https://philosophy.nd.edu/people/faculty/christopher-shields/">Christopher Shields</a>, George N. Shuster Professor of Philosophy, The Aristotelian Tradition</li>
</ul>
<p>Equipment Restoration and Renewal awardees for 2016 are:</p>
<p> </p>
<ul>
<li>
<p><a href="http://physics.nd.edu/people/faculty/daniel-bardayan/">Daniel Bardayan</a>, associate professor of experimental nuclear physics, Restoration and Installation of a World-Class Spectrometer for Nuclear Physics Experiments at the Notre Dame Nuclear Science Laboratory</p>
</li>
<br>
<li>
<br>
<a href="http://artdept.nd.edu/faculty-and-staff/faculty-by-alpha/austin-collins-c-s-c/">Austin Collins, C.S.C.</a>, professor of sculpture in art, art history and design, Sculpture Department Equipment Restoration and Renewal</li>
<br>
<li>
<br>
<a href="http://chemistry.nd.edu/people/masaru-k-kuno/">Ken Kuno</a>, associate professor of chemistry and biochemistry, Notre Dame In-situ Electron Microscopy Laboratory (ND-<span class="caps">IEML</span>) – Beyond Static (materials-, device, and biological-) Imaging</li>
<br>
<li>
<br>
<a href="http://biology.nd.edu/people/michael-pfrender/">Michael Pfrender</a>, associate professor of evolutionary and ecological genomics in biological sciences and director of the genomics and bioinformatics core facility, Renewal of the Notre Dame Next-Generation Sequencing Platform</li>
<br>
<li>
<br>
<a href="https://engineering.nd.edu/profiles/rroeder">Ryan K. Roeder</a>, associate professor of aerospace and mechanical engineering, Acquisition of a Preclinical Spectral Micro-CT System</li>
<br>
<li>
<br>
<a href="http://acms.nd.edu/people/faculty/andrew-sommese/">Andrew Sommese</a>, Vincent J. Duncan and Annamarie Micus Duncan Professor of Mathematics, Renewing our In-Silico Labs: Enabling Computationally Based Simulation and Analysis</li>
</ul>
<p>The 2016 Library Acquisitions grantees are:</p>
<p> </p>
<ul>
<li>
<p><a href="http://artdept.nd.edu/faculty-and-staff/faculty-by-alpha/jean-dibble/">Jean Dibble</a>, professor of printmaking in art, art history and design, Building a Research Collection of Artists’ Books</p>
</li>
<br>
<li>
<br>
<a href="http://history.nd.edu/faculty/directory/patrick-griffin/">Patrick Griffin</a>, Department Chair and Madden-Hennebry Professor of History, Colonial America: The Complete Set of Colonial Office Files for North America, 1606 – 1822 Database</li>
<br>
<li>
<br>
<a href="http://news.nd.edu/news/64570-michel-hockx-scholar-of-chinese-literary-and-internet-culture-appointed-director-of-liu-institute-for-asia-and-asian-studies/">Michel Hockx</a>, professor of Chinese and director of the Liu Institute for Asia and Asian Studies, Pre-1949 Chinese Periodical Full-text Databases</li>
<br>
<li>
<br>
<a href="http://history.nd.edu/faculty/directory/paul-ocobock/">Paul R. Ocobock</a>, assistant professor of history, Preserving and Digitizing the Congregation of the Holy Cross Fort Portal Diocesan Archives, Uganda</li>
</ul>
<p>Notre Dame Research’s Internal Grants Program seeks to support faculty researchers and programs with the goal of advancing the University’s research enterprise. The four grant competitions are announced each year in the fall, with grant deadlines occurring as early as October. For more information about past recipients, how to apply, and more, please visit <a href="https://research.nd.edu/our-services/funding-opportunities/faculty/internal-grants-programs/">https://research.nd.edu/our-services/funding-opportunities/faculty/internal-grants-programs/</a>.</p>
<p>Contact</p>
<p>Brandi R. Klingerman / Research Communications Specialist</p>
<p>Notre Dame Research / University of Notre Dame</p>
<p>bklinger@nd.edu / 574.631.8183</p>
<p><a href="https://research.nd.edu/">research.nd.edu</a> /<a href="https://twitter.com/UNDResearch">@UNDResearch</a></p>
<p>About Notre Dame Research</p>
<p>The University of Notre Dame is a private research and teaching university inspired by its Catholic mission. Located in South Bend, Indiana, its researchers are advancing human understanding through research, scholarship, education, and creative endeavor in order to be a repository for knowledge and a powerful means for doing good in the world. For more information, please see <a href="https://research.nd.edu/">research.nd.edu</a> or <a href="https://twitter.com/UNDResearch">@UNDResearch</a>.</p>
<p class="attribution">Originally published by <span class="rel-author">Brandi Klingerman</span> at <span class="rel-source"><a href="https://research.nd.edu/news/2016-internal-grant-program-awardees-announced/">research.nd.edu</a></span> on <span class="rel-pubdate">May 04, 2016</span>.</p>Brandi Klingermantag:rroeder.nd.edu,2005:News/1027272015-11-05T09:00:00-05:002019-08-14T09:42:26-04:00Dr. Prakash Nallathamby wins Pfizer Young Investigator Poster Award<p>Postdoctoral Research Associate Prakash Nallathamby was awarded a Pfizer Young Investigator Poster Award during a recent retreat held by the Cancer Biology Training Consortium Symposium.</p><p>Postdoctoral Research Associate Prakash Nallathamby was awarded a Pfizer Young Investigator Poster Award during a recent retreat held by the Cancer Biology Training Consortium Symposium.</p>
<p>Dr. Nallathamby, who works with Professor Ryan Roeder of the Department of Aerospace and Mechanical Engineering, is currently working on the modular assembly of surface functionalized core-shell nanoparticles as novel image contrast agents. Dr. Nallathamby is developing a modular approach to design a spectral library of core-shell nanoparticle contrast agents, which will have broad applications in biomedical imaging due to its potential for multi-modal imaging (e.g., fluorescence, MRI, X-ray) and active targeting through molecular surface functionalization. It is anticipated that this modular approach will provide a platform for facile customization of core-shell nanoparticles, for multi-modal imaging probes with tailored surface functionality to target specific cancer subsets.</p>
<p>This research work was presented as a poster at the Cancer Biology Training Consortium (CABTRAC 2015) retreat at Kiawah Island, SC on October 26, 2015. Dr. Nallathamby‘s poster was selected as the top postdoc juried poster and he was awarded the Pfizer Young Investigator Poster Award.</p>
<p>Established in 2005, the <a href="http://cabtrac.org/" target="_blank">Cancer Biology Training Consortium</a> (CABTRAC) facilitates the interdisciplinary exchange of ideas between individuals and institutions that are dedicated training the next generation of cancer researchers. Over 80 institutions US-wide and the National Cancer Institute’s Cancer Training Branch work jointly together in this consortium. Their Cancer Biology Annual Retreat is seen as the premiere Cancer Biology Training conference in the United States to connect today’s and tomorrow’s leaders in cancer research.</p>Nancy Davistag:rroeder.nd.edu,2005:News/1027262015-10-09T09:00:00-04:002019-08-14T09:41:01-04:00Researchers Use Nanotechnology to Fight Breast Cancer<p>October is Breast Cancer Awareness Month, an annual campaign to increase awareness of the disease and the importance of early detection. Researchers at the University of Notre Dame are conducting innovative research aimed at improvements in early detection by molecular imaging.</p><p>October is Breast Cancer Awareness Month, an annual campaign to increase awareness of the disease and the importance of early detection. Researchers at the University of Notre Dame are conducting innovative research aimed at improvements in early detection by molecular imaging.</p>
<p>Professors <a href="https://engineering.nd.edu/profiles/rroeder" target="_blank">Ryan Roeder</a> and <a href="https://engineering.nd.edu/profiles/tvargo-gogola" target="_blank">Tracy Vargo-Gogola</a> are combining their expertise in biomedical engineering and cancer biology, respectively, through the <a href="http://harpercancer.nd.edu/" target="_blank">Harper Cancer Research Institute</a>, a partnership between Notre Dame and the <a href="http://medicine.iu.edu/southbend/" target="_blank">Indiana University School of Medicine-South Bend</a>, to improve the accuracy of mammography for diagnosing breast cancer.</p>
<p>“Early detection is the most proven means to beat breast cancer,” Roeder said. “Mammography is very effective, but not perfect. A specific challenge that has received increased attention in the last few years is that some women have higher breast tissue density, which can mask abnormalities from being detected by mammography. To make matters worse, women with higher breast tissue density are more likely to get breast cancer. Numerous states have now passed legislation requiring that breast tissue density is reported to women who receive mammograms, and federal legislation was recently introduced."</p>
<p>Roeder and Vargo-Gogola’s proposed approach is to deliver a radiographic contrast agent that is able to target abnormalities in breast tissue so that they can be seen by mammography even in dense breast tissue.</p>
<p>“The contrast agent uses gold nanoparticles which have molecules attached that target microcalcifications, which are associated with breast cancer, or antibodies which target tumors themselves,” he said. “This approach would not be done for screening of the general population but for follow-up or high-risk sub-populations. For example, a woman with suspicious findings on a conventional mammogram could receive the contrast agent and a follow-up mammogram to either rule out a false positive, which spares the woman the stress and anxiety of a biopsy procedure, or confirm a true positive with a more sensitive technique. The method could also be particularly helpful for women at high risk based on breast density or genetic screening.”</p>
<p>The research recently received funding from the <a href="https://kellycaresfoundation.org/" target="_blank">Kelly Cares Foundation </a>and the <a href="http://www.sjmed.com/" target="_blank">Saint Joseph Health System</a>.</p>
<p>“We have successfully demonstrated the approach in several preclinical, animal studies,” Roeder said. “The funding we just received from the Kelly Cares Foundation will allow us to investigate feasibility in human-scale models and imaging instrumentation at the Saint Joseph Regional Medical Center in order to build a case for pursuing a clinical trial.”</p>
<p>Although early results of the research have shown that much smaller lesions are being detected using the approach, Roeder and Vargo-Gogola caution that more research remains to be done.</p>
<p>“A clinical trial is realistically at least two years away, and if successful, patients would not widely benefit for at least several more years,” Roeder said.</p>
<p>“Unfortunately, research is very costly and time-consuming, but the potential pay-off is immeasurable if we can save more lives.”</p>
<p><br>
Contact: Ryan K. Roeder, 574-631-7003, <a href="mailto:rroeder@nd.edu?subject=Nanotechnology%20to%20fight%20breast%20cancer">rroeder@nd.edu</a></p>
<p><em>— William Gilroy, Office of Media Relations</em></p>
<p> </p>
<p>Click <a href="https://engineering.nd.edu/highlights/the-transformation-of-cancer-imaging-from-shades-of-gray-to-living-color#sthash.WeHCiw0v.4DbHMsaU.dpbs" target="_blank">here</a> for more information on additional research being conducted by Roeder and Vargo-Gogola to combat cancer via biomedical imaging.</p>William Gilroytag:rroeder.nd.edu,2005:News/1027242015-09-30T09:00:00-04:002019-08-14T09:37:57-04:00The Transformation of Cancer Imaging: From Shades of Gray to Living Color<p>Promising a transformation in biomedical imaging, a new technology called spectral [color] computed tomography is at work on the University of Notre Dame’s campus, where researchers are giving the phrase “in living color” a new meaning.</p><p>Taken by Wilhelm Roentgen in 1895, the first X-ray produced was of his wife’s hand. Roentgen received the first Nobel Prize in physics for his work, but his discovery of X-ray beams also changed the medical profession far more than that simple black-and-white image might have suggested. The beams he used, higher in frequency than ultraviolet light but lower in frequency than gamma rays, revolutionized the medical profession, allowing physicians to see inside a patient’s body to more readily to diagnose disease and injury.<br>
<br>
In short, Roentgen laid the foundation for diagnostic radiology. Within six months of his discovery, surgeons on the battlefield were using X-rays to locate bullets in wounded soldiers. Since that time they have continued to be used — for non-invasive imaging in biomedicine, non-destructive testing of materials, security screening, and more. The technology has advanced and so has the clarity and accuracy of the X-rays. <br>
<br>
Today radiographic images, such as X-rays, mammograms, and computed tomography (CT), help detect diseases like cancer in its early stages when treatment can be most effective. However, it has all been in black-and-white. Even accounting for the remarkable advances in radiography and 3-D imaging since Roentgen, the difference between healthy tissue and abnormalities can be difficult to detect when an image is in shades of gray. Unfortunately, it can still be the difference between life and death.</p>
<p>A new technology called spectral [color] computed tomography (spectral CT) is not only on the horizon, but it is also on the University of Notre Dame’s campus, where researchers are giving the phrase “in living color” a new meaning. <br>
<br>
According to project leaders <a href="https://engineering.nd.edu/profiles/rroeder" target="_blank">Ryan K. Roeder</a>, associate professor of aerospace and mechanical engineering, and <a href="https://engineering.nd.edu/profiles/tvargo-gogola" target="_blank">Tracy C. Vargo-Gogola</a>, senior lecturer in biochemistry and molecular biology with <a href="http://medicine.iu.edu/southbend/" target="_blank">Indiana University School of Medicine at South Bend</a> and the <a href="http://harpercancer.nd.edu/" target="_blank">Harper Cancer Research Institute</a>, the spectral CT they are using — part of a collaboration between Notre Dame and <a href="http://www.marsbioimaging.com/mars/" target="_blank">MARS Bioimaging Ltd. (MBI)</a> — is the first commercially-available preclinical system in the United States. Housed in the <a href="http://ndiif.nd.edu/" target="_blank">Notre Dame Integrated Imaging Facility (NDIIF)</a>, the MBI preclinical spectral CT scanner can detect up to eight X-ray energy channels simultaneously, allowing color assignment to specific molecular signatures for improved identification of abnormalities, such as tumors. “The technology promises a transformation for biomedical imaging in general and cancer imaging in particular,” says Professor <a href="http://chemistry.nd.edu/people/bradley-d-smith/" target="_blank">Bradley Smith</a>, the Emil T. Hofman Professor of Chemistry and Biochemistry and director of the NDIIF.</p>
<p>While the scanner uses advanced X-ray detector technology [made possible by the Medipix3 detector chip developed at the CERN], it is aided by nanoparticle contrast agents that Roeder’s lab has created to “target” molecular signatures associated with cancer and other diseases. Individual contrast agents and tissue types can be identified and assigned a specific color, resulting in a more complete picture than ever realized.</p>
<p>Roeder, Vargo-Gogola, and their team are presently investigating spectral CT contrast agents for molecular imaging with support from the National Science Foundation. Their research is also being incorporated into a variety of educational programs for students engaging in STEM disciplines through NDnano and the Harper Cancer Research Institute.</p>
<p>In addition, the researchers are forming a close collaboration with the Kelly Cares Foundation and the Saint Joseph Health System to develop more accurate breast cancer detection methods using molecular imaging for women with dense breast tissue using various molecular imaging approaches, including spectral CT. While these efforts focus on breast cancer, work with this new molecular X-ray scanner is promising for the detection and treatment of many types of cancers, including ovarian, colorectal, lung, and metastatic disease.</p>Nancy Davistag:rroeder.nd.edu,2005:News/1027232015-09-18T09:35:00-04:002019-08-14T09:36:13-04:00New Approach to Mammograms Could Improve Reliability<p>A recent article in the journal ASC Nano describes a process using targeted gold nanoparticles: "Detecting breast cancer in women with dense mammary tissues could become more reliable with a new mammogram procedure that researchers have now tested in pre-clinical studies of mice."</p><p>Detecting breast cancer in women with dense mammary tissues could become more reliable with a new mammogram procedure that researchers have now tested in pre-clinical studies of mice. <a href="http://pubs.acs.org/doi/abs/10.1021/acsnano.5b02749" target="_blank">In their report in the journal <em>ACS Nano</em></a>, they describe injecting gold nanoparticles in mammary tissue to enhance the imaging of early signs of breast cancer.<br>
<br>
Mammography remains the clinical gold standard of screening tests for detecting breast cancer. However, a recognized limitation of this X-ray procedure is that dense breast tissue shows up as white masses and fibers on an image, which can obscure the presence of microcalcifications — potential signs of early cancer development. Other imaging methods including ultrasound, magnetic resonance imaging and molecular breast imaging can also find abnormalities, but each has its own limitation, such as high cost or poor resolution. <a href="https://engineering.nd.edu/profiles/lcole" target="_blank">Lisa Cole</a>, <a href="https://engineering.nd.edu/profiles/tvargo-gogola" target="_blank">Tracy Vargo-Gogola</a> and <a href="https://engineering.nd.edu/profiles/rroeder" target="_blank">Ryan K. Roeder</a> wanted to improve patients’ options.<br>
<br>
The researchers boosted the contrast of mammography X-rays by modifying gold nanoparticles with molecules that bind specifically to microcalcifications. They injected a low dose of these nanoparticles into the mammary glands of mice with dense tissue. The engineered particles made the microcalcifications brighter on the X-rays — and therefore, easier to distinguish. The mice showed no obvious side effects. Although further research would be required, the scientists say the technique could eventually translate into more reliable breast cancer detection for women with dense mammary tissue.<br>
<br>
The authors acknowledge funding from the <a href="http://www.sjmed.com/" target="_blank"><em>St. Joseph Regional Medical Center</em></a>, the <a href="http://www.walther.org/" target="_blank">Walther Cancer Foundation</a> and the <a href="http://www.nsf.gov/" target="_blank">National Science Foundation</a>.</p>
<p><em>— ACS News Service Weekly, September 16, 2015</em></p>ASC News Service Weeklytag:rroeder.nd.edu,2005:News/1027222015-06-18T09:00:00-04:002019-08-14T09:34:38-04:00News items from 2002 to 2007<p>A listing of links to news articles from the lab between 2002 and 2007.</p><h2>2007</h2>
<p>Justin Deuerling took 2nd place for his oral presention (<a href="http://www3.nd.edu/~rroeder/publications/2007%20SBC%20Deuerling.pdf" target="_blank">abstract</a>) and Matt Landrigan received honorable mention for his poster (<a href="http://www3.nd.edu/~rroeder/publications/2007%20SBC%20Landrigan.pdf" target="_blank">abstract</a>) in the PhD Student Paper Competition at the <a href="http://divisions.asme.org/bed/events/summer07.html" target="_blank">2007 Summer Bioengineering Conference</a> sponsored by the <a href="http://divisions.asme.org/bed/" target="_blank">Bioengineering Division</a> (BED) of the<a href="http://www.asme.org/" target="_blank">American Society of Mechanical Engineers</a> (ASME)</p>
<p>Gabriel L. Converse wins <a href="http://kaneb.nd.edu/ta/awards/2007TAawards.pdf" target="_blank">Outstanding Graduate Student Teacher Award</a>from the <a href="http://kaneb.nd.edu/" target="_blank">Kaneb Center</a> at the University of Notre Dame.</p>
<p>Roeder wins the <a href="http://www.tms.org/newsletter/archive/0606.asp#Roeder" target="_blank">Early Career Faculty Fellow Award</a> from the <a href="http://www.tms.org/" target="_blank">The Minerals, Metals and Materials Society</a> (TMS). (<a href="http://newsinfo.nd.edu/content.cfm?topicid=18183" target="_blank">ND press release</a>, <a href="http://www.nd.edu/~engineer/publications/signatures/2007/takingnote/inaugural.html" target="_blank">Signatures</a>)</p>
<p>Research on imaging microdamage in bone featured in <a href="http://www.nd.edu/~engineer/publications/signatures/2007/medimaging/bonemass.html" target="_blank">Signatures</a>.</p>
<h2>2006</h2>
<p>Faculty move into new building dedicated to bioengineering research. (<a href="http://newsinfo.nd.edu/content.cfm?topicId=10922" target="_blank">ND press release</a>, <a href="http://www.nd.edu/~engineer/publications/signatures/2006/changes.html" target="_blank">Signatures</a>)</p>
<p>Weimin Yue wins <a href="http://kaneb.nd.edu/ta/awards/2006TAawards.pdf" target="_blank">Outstanding Graduate Student Teacher Award</a> from the<a href="http://kaneb.nd.edu/" target="_blank">Kaneb Center</a> at the University of Notre Dame.</p>
<p>Awarded a four year grant from the Department of Defense Peer Reviewed Medical Research Program (PR054672) funded through the <a href="https://mrmc-www.army.mil/" target="_blank">U.S. Army Medical Research and Materiel Command</a> (USAMRMC W81XWH-06-1-0196) to study "Contrast Agents for Micro-Computed Tomography of Microdamage in Bone."</p>
<h2>2005</h2>
<p>Huijie Leng wins Graduate Student Award at the Fall Meeting of the<a href="http://www.mrs.org/" target="_blank">Materials Research Society</a>.</p>
<h2>2004</h2>
<p>Awarded subcontract from Granger Engineering (<a href="http://www.nsf.gov/" target="_blank">NSF</a> STTR Phase I and<a href="http://www.21fund.org/" target="_blank">Indiana 21st Century Fund</a>) to study variable diameter fibers for biocomposites.</p>
<h2>2002</h2>
<p>Awarded a three year grant from the <a href="http://www.nih.gov/" target="_blank">National Institutes for Health</a> (NIH NIAMS R21 <a href="http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=6579620&p_grant_num=1R21AR049598-01&p_query=&ticket=37409488&p_audit_session_id=239679351&p_keywords=" target="_blank">AR049598</a>) to study "Staining Techniques for Micro-CT Imaging of Microdamage."</p>
<p>Research featured in <a href="http://www.nd.edu/~ndmag/au2002/skeletal.html" target="_blank">Notre Dame Magazine</a> and <a href="http://www.nd.edu/~engineer/publications/signatures/2002/quality.html" target="_blank">Signatures</a>.</p>Ryan Roeder